Fcα Receptor Type I and Its Association with Atherosclerosis Development

Objectives Atherosclerosis is a chronic inflammatory disease characterized by lipid accumulation and local inflammation, which are regulated the immune system. The immunological aspects of this unclear. Immunoglobulin A regulates many cell responses through interactions with Fcα receptor type I (FcαRI). Anti-FcαRI antibody inhibits activating receptors inducing an inhibitory immunoreceptor tyrosine-based activation motif configuration. However, role FcαRI in atherosclerosis development Here, we investigated utility targeting to induce signaling treatment.